Parathyroid Hormone Secretion Is Controlled by Both Ionized Calcium and Phosphate During Exercise and Recovery in Men

What Was Tested

The paper reports a study of Parathyroid Hormone (PTH 1-84), published as a randomized controlled trial.

The objective of the study was to examine the temporal pattern of PTH, PO4, albumin-adjusted calcium, and Ca(2+) during and after exercise.

Why It Was Studied

The mechanism by which PTH is controlled during and after exercise is poorly understood due to insufficient temporal frequency of measurements.

Who Took Part

By PubMed's age tags, the people studied were young adults and adults, men only.

Ten men (aged 23 ± 1 y, height 1.82 ± 0.07 m, body mass 77.0 ± 7.5 kg) participated.

How the Study Was Run

The design is described as randomized and crossover.

The participants were allocated by chance, so the Parathyroid Hormone (PTH 1-84) group and the comparison group should start out alike.

Each person switched between Parathyroid Hormone (PTH 1-84) and the comparison at some point, usually with a gap in between.

Blood was obtained at baseline, after 2.5, 5, 7.5, 10, 15, 20, 25, and 30 minutes of exercise, and after 2.5, 5, 7.5, 10, 15, 20, 25, 30, 60, 90, and 150 minutes of recovery.

What Was Measured

The mechanism by which PTH is controlled during and after exercise is poorly understood due to insufficient temporal frequency of measurements.

Topics PubMed links to this paper include Calcium, Exercise, Exercise Test, Ions, Oxygen Consumption, Parathyroid Hormone and Phosphates.

What This Means in Plain Language

The paper is a randomized and crossover study of Parathyroid Hormone (PTH 1-84).

Results are reported in around 7 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2016 (The Journal of clinical endocrinology and metabolism), a journal based in United States.

More context: the Parathyroid Hormone (PTH 1-84) compound page, all human trials.