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Vitamin D Metabolism Varies among Women in Different Reproductive States Consuming the Same Intakes of Vitamin D and Related Nutrients.
Plain-language guide to PMID 27335139 (2016): randomized controlled trial of Vitamin D, K2, Magnesium and Zinc.
Key Facts
- PMID
- 27335139
- Journal
- The Journal of nutrition
- Year
- 2016
- Study type
- Randomized Controlled Trial
- Authors
- Park H et al. (9 authors)
- DOI
- 10.3945/jn.116.229971
- Registered trial
- NCT01127022
What This Study Did, in Plain Language
What Was Tested
Researchers studied Vitamin D, K2, Magnesium and Zinc in this randomized controlled trial publication.
The researchers aimed to quantify the impact of the reproductive state on a panel of vitamin D biomarkers among women of childbearing age consuming equivalent amounts of vitamin D and related nutrients.
Why It Was Studied
The impact of the reproductive state on vitamin D metabolism and requirements is uncertain in part because of a lack of studies with controlled dietary intakes of vitamin D and related nutrients.
Who Took Part
By PubMed's age tags, the people studied were adults, women only.
How the Study Was Run
The design is described as randomized.
The participants were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.
Vitamin D biomarkers were measured in blood obtained at baseline and study end, and differences in biomarker response among the reproductive groups were assessed with linear mixed models adjusted for influential covariates (e.g., body mass index, season, race/ethnicity).
What Was Measured
Topics PubMed links to this paper include Biomarkers, Cholecalciferol, Diet, Dietary Supplements, Energy Intake, Lactation and Reproduction.
The authors tagged it with the keywords 1,25-dihydroxyvitamin D, 24,25-dihydroxyvitamin D, 25(OH)D:24,25(OH)2D ratio, 25-hydroxyvitamin D, Epi-25(OH)D3 and free 25(OH)D.
What This Means in Plain Language
The paper is a randomized study of Vitamin D, K2, Magnesium and Zinc.
Results are reported in around 7 sentences of the abstract; we leave them to the paper itself rather than summarise them.
The publication is from 2016 (The Journal of nutrition), a journal based in United States.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.