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[Vitamin D deficiency in children admitted to the paediatric intensive care unit].

Plain-language guide to PMID 27381433 (2017): observational study of Vitamin D, K2, Magnesium and Zinc in 90 children.

Key Facts

PMID
27381433
Journal
Revista chilena de pediatria
Year
2017
Study type
Observational Study
Authors
Bustos B R et al. (4 authors)
DOI
10.1016/j.rchipe.2016.05.008

What This Study Did, in Plain Language

What Was Tested

The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as an observational study.

To establish the prevalence of VDD and its association with clinically relevant outcomes in children admitted to a Paediatric Intensive Care Unit (PICU) in Concepcion, Chile.

Relative risks (RR) were calculated to determine the association between VDD and relevant clinical outcomes.

Why It Was Studied

Vitamin D is essential for bone health, as well as for cardiovascular and immune function.

Who Took Part

According to the abstract, 90 children were involved.

PubMed indexes the participants as young children, both men and women.

Prospective observational cohort study in 90 consecutive children admitted to the PICU in a university general hospital.

How the Study Was Run

Blood was collected on admission to PICU and analysed for 25-OH-D levels.

Severity of illness and vasopressor use were assessed using PRISM, PELOD, and vasoactive-inotropic score (VIS) score.

VDD was defined as a serum 25-OH-D level<20ng/ml.

What Was Measured

Topics PubMed links to this paper include Chile, Cohort Studies, Critical Illness, Intensive Care Units, Pediatric, Prevalence, Vasoconstrictor Agents and Vitamin D.

The authors tagged it with the keywords Children, Cuidado intensivo pediátrico, Niños, Paediatric intensive care, Sepsis and Vitamina D.

What This Means in Plain Language

This is an observational study of Vitamin D, K2, Magnesium and Zinc in 90 children.

Its findings take up roughly 5 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2017 (Revista chilena de pediatria), a journal based in Chile.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.