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Association Between Vitamin D Deficiency and Outcomes Following Spinal Fusion Surgery: A Systematic Review.

Plain-language guide to PMID 27481599 (2016): systematic review of Vitamin D, K2, Magnesium and Zinc.

Key Facts

PMID
27481599
Journal
World neurosurgery
Year
2016
Study type
Systematic Review
Authors
Kerezoudis P et al. (7 authors)
DOI
10.1016/j.wneu.2016.07.074

What This Paper Covers, in Plain Language

What It Covers

This systematic review looks at Vitamin D, K2, Magnesium and Zinc.

Vitamin D deficiency is a relatively common occurrence in patients presenting for spinal surgery; however, whether this abnormality has any effect on spinal fusion outcomes remains unclear.

The researchers performed a systematic review of the available literature relevant to the association between vitamin D deficiency and spinal fusion outcomes.

How the Review Was Done

The researchers conducted a systematic and critical review of recent literature following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines.

The following databases were searched: MEDLINE/PubMed, Google Scholar, Cochrane, Web of Science, and Scopus.

Key search terms were "vitamin D," "spinal surgery outcomes," "spinal fusion," and "pseudarthrosis." Papers included in the review were original research articles in peer-reviewed journals.

The articles were thoroughly examined and compared on the basis of study design, outcomes, and results.

What Was Measured

Vitamin D deficiency is a relatively common occurrence in patients presenting for spinal surgery; however, whether this abnormality has any effect on spinal fusion outcomes remains unclear.

The researchers performed a systematic review of the available literature relevant to the association between vitamin D deficiency and spinal fusion outcomes.

PubMed files the paper under topics including Back Pain, Patient Reported Outcome Measures, Postoperative Complications, Pseudarthrosis, Spinal Diseases, Spinal Fusion and Vitamin D Deficiency.

The authors tagged it with the keywords Osteomalacia, Spinal surgery and Surgical outcomes.

What This Means in Plain Language

This is a systematic review of Vitamin D, K2, Magnesium and Zinc.

Its findings take up roughly 5 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2016 (World neurosurgery), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.