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Vitamin D-enhanced eggs are protective of wintertime serum 25-hydroxyvitamin D in a randomized controlled trial of adults.

Plain-language guide to PMID 27488236 (2016): randomized controlled trial of Vitamin D, K2, Magnesium and Zinc.

Key Facts

PMID
27488236
Journal
The American journal of clinical nutrition
Year
2016
Study type
Randomized Controlled Trial
Authors
Hayes A et al. (12 authors)
DOI
10.3945/ajcn.116.132530
Registered trial
NCT02678364

What This Study Did, in Plain Language

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc in this randomized controlled trial publication.

The researchers performed a randomized controlled trial (RCT) to investigate the effect of the consumption of vitamin D-enhanced eggs (produced by feeding hens at the maximum concentration of vitamin D3 or serum 25-hydroxyvitamin D [25(OH)D3] lawfully allowed in feed) on winter serum 25(OH)D in healthy adults.

Why It Was Studied

Despite numerous animal studies that have illustrated the impact of additional vitamin D in the diet of hens on the resulting egg vitamin D content, the effect of the consumption of such eggs on vitamin D status of healthy individuals has not, to their knowledge, been tested.

Who Took Part

By PubMed's age tags, the people studied were middle-aged adults and older adults, both men and women.

The researchers conducted an 8-wk winter RCT in adults aged 45-70 y (n = 55) who were stratified into 3 groups and were requested to consume ≤2 eggs/wk (control group, in which status was expected to decline), 7 vitamin D3-enhanced eggs/wk, or seven 25(OH)D3-enhanced eggs/wk.

How the Study Was Run

In design terms this was a randomized study.

Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

Serum 25(OH)D was the primary outcome.

What Was Measured

Despite numerous animal studies that have illustrated the impact of additional vitamin D in the diet of hens on the resulting egg vitamin D content, the effect of the consumption of such eggs on vitamin D status of healthy individuals has not, to their knowledge, been tested.

PubMed files the paper under topics including 25-Hydroxyvitamin D 2, Calcifediol, Chickens, Cholecalciferol, Consumer Behavior, Cooking and Diet.

Author keywords: 25(OH)D, RCT, bioaddition, vitamin D deficiency and vitamin D–enhanced eggs.

What This Means in Plain Language

The paper is a randomized study of Vitamin D, K2, Magnesium and Zinc.

The abstract goes on to report its results in about 5 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2016 (The American journal of clinical nutrition), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.