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Effect of vitamin D3 supplementation on iron status: a randomized, double-blind, placebo-controlled trial among ethnic minorities living in Norway.
Plain-language guide to PMID 27506667 (2016): double-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc in 251 participants.
Key Facts
- PMID
- 27506667
- Journal
- Nutrition journal
- Year
- 2016
- Study type
- Randomized Controlled Trial
- Authors
- Madar AA et al. (6 authors)
- DOI
- 10.1186/s12937-016-0192-7
What This Study Did, in Plain Language
What Was Tested
This randomized controlled trial looks at Vitamin D, K2, Magnesium and Zinc.
However, there is a paucity of randomised controlled trials assessing the effect of vitamin D supplementation on iron status.
Who Took Part
The abstract describes 251 participants taking part.
PubMed indexes the participants as teenagers, young adults, adults and middle-aged adults, both men and women.
How the Study Was Run
The researchers set it up as a randomized, double-blind and placebo-controlled study.
Random assignment meant chance, not the researchers, decided who got Vitamin D, K2, Magnesium and Zinc and who got the comparison, which limits bias.
Neither the participants nor the staff measuring them knew who was on Vitamin D, K2, Magnesium and Zinc, so expectations could not easily colour the readings.
The comparison arm used a placebo, so changes seen with Vitamin D, K2, Magnesium and Zinc could be set against what happens without it.
What Was Measured
However, there is a paucity of randomised controlled trials assessing the effect of vitamin D supplementation on iron status.
PubMed files the paper under topics including Anemia, Iron-Deficiency, Asia, C-Reactive Protein, Cholecalciferol, Dietary Supplements, Ethnicity and Ferritins.
The authors tagged it with the keywords Immigrants, Iron status, Randomised controlled trials and Vitamin D.
What This Means in Plain Language
The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc in 251 participants.
Its findings take up roughly 3 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.
The publication is from 2016 (Nutrition journal), a journal based in England.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.