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Vitamin D supplementation during pregnancy on infant anthropometric measurements and bone mass of mother-infant pairs: A randomized placebo clinical trial.
Plain-language guide to PMID 27513714 (2016): randomized controlled trial of Vitamin D, K2, Magnesium and Zinc and Copper (Supplement).
Key Facts
- PMID
- 27513714
- Journal
- Early human development
- Year
- 2016
- Study type
- Randomized Controlled Trial
- Authors
- Vaziri F et al. (5 authors)
- DOI
- 10.1016/j.earlhumdev.2016.07.011
What This Study Did, in Plain Language
What Was Tested
This randomized controlled trial looks at Vitamin D, K2, Magnesium and Zinc and Copper (Supplement).
Based on the essential role of vitamin D in the regulation of calcium metabolism, the researchers evaluated the effects of 2000IUvitamin D/day in late pregnancy on infant's anthropometric measurements and bone mass parameters of mother-infant pairs.
Who Took Part
The age groups tagged for this paper are adults, both men and women.
In this randomized clinical trial, the main inclusion criteria were: aged 18 or older, no history of internal diseases and pregnancy complications, and a singleton live fetus.
Maternal serum 25-hydroxyvitamin D, infants' anthropometric measurements (at birth, 4th and 8th weeks postnatal), and maternal and infant bone mass parameters were examined.
How the Study Was Run
The design is described as randomized.
Random assignment meant chance, not the researchers, decided who got Vitamin D, K2, Magnesium and Zinc and who got the comparison, which limits bias.
What Was Measured
Based on the essential role of vitamin D in the regulation of calcium metabolism, the researchers evaluated the effects of 2000IUvitamin D/day in late pregnancy on infant's anthropometric measurements and bone mass parameters of mother-infant pairs.
Topics PubMed links to this paper include Birth Weight, Bone Demineralization, Pathologic, Bone Density, Fetal Development, Pregnancy Complications, Vitamin D and Vitamins.
Author keywords: Infant body measurements, Infant bone mass, Maternal bone mass and Vitamin D supplement.
What This Means in Plain Language
The paper is a randomized study of Vitamin D, K2, Magnesium and Zinc and Copper (Supplement).
Results are reported in around 7 sentences of the abstract; we leave them to the paper itself rather than summarise them.
The publication is from 2016 (Early human development), a journal based in Ireland.
More context: the Vitamin D, K2, Magnesium and Zinc compound page and the Copper (Supplement) compound page, all human trials.
Our Notes on the Compounds
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Copper (Supplement): The active site of cytochrome c oxidase is described as containing copper ions that are essential for electron transfer.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.