Comparison of Vitamin D Levels in Patients with and without Acne: A Case-Control Study Combined with a Randomized Controlled Trial.

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc in the context of acne in this randomized controlled trial publication.

The researchers evaluated vitamin D levels in patients with acne to determine the effect of vitamin D supplementation.

Why It Was Studied

Vitamin D plays an important role in the immune system, and its deficiency has been implicated in various skin diseases, including atopic dermatitis and psoriasis.

Acne is a common inflammatory skin disease; however, the association with vitamin D remains unclear.

Who Took Part

The abstract describes 80 patients taking part.

PubMed indexes the participants as teenagers, young adults and adults, both men and women.

This study included 80 patients with acne and 80 healthy controls.

How the Study Was Run

In design terms this was a randomized study.

The patients were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.

Serum 25-hydroxyvitamin D (25(OH)D) levels were measured, and demographic data were collected.

What Was Measured

The subject headings attached to it are Acne Vulgaris, Case-Control Studies, Dietary Supplements, Immune System, Inflammation, Vitamin D and Vitamin D Deficiency.

What This Means in Plain Language

The paper is a randomized study of Vitamin D, K2, Magnesium and Zinc in 80 patients in people with acne.

The abstract goes on to report its results in about 4 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2016 (PloS one), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, Acne research.