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Vitamin D status in cervical spondylotic myelopathy: comparison of fusion rates and patient outcome measures.

Plain-language guide to PMID 27588820 (2019): observational study of Vitamin D, K2, Magnesium and Zinc.

Key Facts

PMID
27588820
Journal
Journal of neurosurgical sciences
Year
2019
Study type
Observational Study
Authors
Ravindra VM et al. (9 authors)
DOI
10.23736/S0390-5616.16.03846-7

What This Study Did, in Plain Language

What Was Tested

The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as an observational study.

Patients undergoing elective spinal fusion have an alarming rate of vitamin D deficiency, but its impact on bone fusion and patient outcomes is unclear.

The researchers investigated the association of perioperative vitamin D levels, fusion rates, and patient-reported outcome in patients undergoing spinal fusion for cervical spondylotic myelopathy.

Who Took Part

The age groups tagged for this paper are adults, middle-aged adults and older adults, both men and women.

In this one-year, prospective, single-center observational study, serum 25-OH vitamin D levels were measured perioperatively in adult patients.

The primary outcome measures were postoperative patient-reported outcomes (Neck Disability Index, Visual Analog Scale, EuroQol EQ-5D-3L, EQ-VAS).

How the Study Was Run

Serum vitamin D levels <30 ng/mL were considered abnormal.

Secondary outcome measures were the presence of and time to solid bony fusion, controlling for Body Mass Index (BMI), age, and number of motion segments.

What Was Measured

Patients undergoing elective spinal fusion have an alarming rate of vitamin D deficiency, but its impact on bone fusion and patient outcomes is unclear.

The researchers investigated the association of perioperative vitamin D levels, fusion rates, and patient-reported outcome in patients undergoing spinal fusion for cervical spondylotic myelopathy.

PubMed files the paper under topics including Elective Surgical Procedures, Hydroxycholecalciferols, Outcome Assessment, Health Care, Postoperative Complications, Spinal Cord Diseases, Spinal Fusion and Spondylosis.

What This Means in Plain Language

This is an observational study of Vitamin D, K2, Magnesium and Zinc.

The abstract goes on to report its results in about 6 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2019 (Journal of neurosurgical sciences), a journal based in Italy.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.