Elevations in growth hormone and glucagon-like peptide-2 levels on admission are associated with increased mortality in trauma patients.

What Was Tested

Researchers studied Exogenous HGH, sermorelin & older GHRPs (why they're passed over) and Glucagon in this observational study publication.

To investigate the utility of GH and other endocrine responses in the prediction of outcomes, the researchers conducted a prospective, observational study of adult burn and trauma patients.

Why It Was Studied

Burn and trauma patients present a clinical challenge due to metabolic derangements and hypermetabolism that result in a prolonged catabolic state with impaired healing and secondary complications, including ventilator dependence.

Who Took Part

By PubMed's age tags, the people studied were adults and middle-aged adults, both men and women.

What Was Measured

Burn and trauma patients present a clinical challenge due to metabolic derangements and hypermetabolism that result in a prolonged catabolic state with impaired healing and secondary complications, including ventilator dependence.

The subject headings attached to it are Glucagon-Like Peptide 2, Hospitalization, Human Growth Hormone, Insulin-Like Growth Factor Binding Protein 3, Insulin-Like Growth Factor I, Predictive Value of Tests and Prognosis.

The authors tagged it with the keywords Biomarker, Burn, Hypermetabolism and Trauma.

What This Means in Plain Language

This is an observational study of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) and Glucagon.

The abstract goes on to report its results in about 4 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2016 (Scandinavian journal of trauma, resuscitation and emergency medicine), a journal based in England.

More context: the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) compound page and the Glucagon compound page, all human trials.