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Quit Intentions Moderate Subjective and Physiological Responses to Acute Nicotine Replacement Therapy Administration in Dependent Smokers.

Plain-language guide to PMID 27838660 (2017): randomized controlled trial of Therapeutic nicotine (patch, non-peptide).

Key Facts

PMID
27838660
Journal
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco
Year
2017
Study type
Randomized Controlled Trial
Authors
Schlagintweit HE et al. (3 authors)
DOI
10.1093/ntr/ntw307

What This Study Did, in Plain Language

What Was Tested

The paper reports a study of Therapeutic nicotine (patch, non-peptide), published as a randomized controlled trial.

This study assessed the impact of expectancy and administration components of acute nicotine inhaler use on craving, heart rate, and smoking behavior in smokers with varying intentions to quit.

Who Took Part

PubMed indexes the participants as adults.

Next, participants were offered an opportunity to self-administer puffs of their preferred tobacco brand during an hour-long progressive ratio task.

How the Study Was Run

The researchers set it up as a randomized study.

Because people in this Therapeutic nicotine (patch, non-peptide) study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

Instructions regarding the inhaler's nicotine content (expect nicotine vs. expect nicotine-free; nicotine expectancy) and flavor (mint vs. citrus) varied across sessions.

Craving and heart rate were assessed before and after inhaler administration (two-second inhalations every 10 seconds over 20 minutes).

What Was Measured

This study assessed the impact of expectancy and administration components of acute nicotine inhaler use on craving, heart rate, and smoking behavior in smokers with varying intentions to quit.

The subject headings attached to it are Craving, Health Behavior, Heart Rate, Intention, Motivation, Nicotine and Smokers.

What This Means in Plain Language

The paper is a randomized study of Therapeutic nicotine (patch, non-peptide).

Its findings take up roughly 8 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2017 (Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco), a journal based in England.

More context: the Therapeutic nicotine (patch, non-peptide) compound page, all human trials.

Our Notes on the Compound

Therapeutic nicotine (patch, non-peptide): Pure nicotine as a signaling tool, separated from smoking and vaping.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.