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Recovery responses of testosterone, growth hormone, and IGF-1 after resistance exercise.

Plain-language guide to PMID 27856715 (2017): review of IGF-1 LR3 and Exogenous HGH, sermorelin & older GHRPs (why they're passed over).

Key Facts

PMID
27856715
Journal
Journal of applied physiology (Bethesda, Md. : 1985)
Year
2017
Study type
Review
Authors
Kraemer WJ et al. (3 authors)
DOI
10.1152/japplphysiol.00599.2016

What This Paper Covers, in Plain Language

What It Covers

Researchers studied IGF-1 LR3 and Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in this review publication.

The purpose of this review is to examine the role of resistance exercise (RE) on the recovery responses of three major anabolic hormones, testosterone, growth hormone(s), and insulin-like growth factor 1.

Why It Was Studied

The complexity and redundancy of the endocrine pathways during recovery related to anabolic function in the body belie an oversimplistic approach to its study.

Each hormone has a complexity related to differential pathways of action as well as interactions with binding proteins and receptor interactions.

Who the Included Studies Covered

The age groups tagged for this paper are young adults, men only.

What Was Measured

Testosterone is the primary anabolic hormone, and its concentration changes during the recovery period depending on the upregulation or downregulation of the androgen receptor.

PubMed files the paper under topics including Adaptation, Physiological, Exercise, Human Growth Hormone, Insulin-Like Growth Factor I, Muscle Fatigue, Muscle, Skeletal and Recovery of Function.

The authors tagged it with the keywords anabolic hormones, humans and strength training.

What This Means in Plain Language

This is a review of IGF-1 LR3 and Exogenous HGH, sermorelin & older GHRPs (why they're passed over).

The publication is from 2017 (Journal of applied physiology (Bethesda, Md. : 1985)), a journal based in United States.

More context: the IGF-1 LR3 compound page and the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) compound page, all human trials.

Our Notes on the Compounds

IGF-1 LR3: A modified IGF-1 analog that escapes binding proteins, so it stays active ≥24 h.

Exogenous HGH, sermorelin & older GHRPs (why they're passed over): Constant levels suppress the body's own GHRH, raise somatostatin and dull pituitary response.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.