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The Effects of Dietary Calcium Supplements Alone or With Vitamin D on Cholesterol Metabolism: A Meta-Analysis of Randomized Controlled Trials.
Plain-language guide to PMID 27870724 (2018): meta-analysis of Vitamin D, K2, Magnesium and Zinc.
Key Facts
- PMID
- 27870724
- Journal
- The Journal of cardiovascular nursing
- Year
- 2018
- Study type
- Meta-Analysis
- Authors
- Chen C et al. (6 authors)
- DOI
- 10.1097/JCN.0000000000000379
What This Paper Covers, in Plain Language
What It Covers
The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a meta-analysis.
The aim of this study is to conduct a meta-analysis of controlled clinical trials that have examined the effects of calcium supplements on blood lipids among adults.
Why It Was Studied
Evidence supports the role of lifestyle interventions as a primary intervention strategy among individuals with dyslipidemia.
The role of micronutrients, and calcium in particular, on cholesterol metabolism is not clear and warrants further investigation.
Who the Included Studies Covered
The age groups tagged for this paper are adults.
MEDLINE, EMBASE, Web of Science, and Cochrane Central Register of Controlled Trials databases were searched up to March 2016 for calcium supplements clinical trials.
Clinical trials with random allocation to calcium supplementation or calcium plus vitamin D supplementation, or control were selected.
How the Review Was Done
Other trials were selected from searching bibliography of reviews, meta-analysis, and included trials.
Data collected included study design, participant characteristics, information of the intervention, and outcomes.
Data synthesis was conducted using random effect models.
What Was Measured
Evidence supports the role of lifestyle interventions as a primary intervention strategy among individuals with dyslipidemia.
Topics PubMed links to this paper include Calcium, Dietary, Cholesterol, LDL, Dietary Supplements, Randomized Controlled Trials as Topic, Vitamin D, Vitamin D Deficiency and Vitamins.
What This Means in Plain Language
This is a meta-analysis of Vitamin D, K2, Magnesium and Zinc.
The abstract goes on to report its results in about 5 sentences; this page does not restate them, so read the paper for the findings and their limits.
The publication is from 2018 (The Journal of cardiovascular nursing), a journal based in United States.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.