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Evaluation of cardiac function in a group of small for gestational age school-age children treated with growth hormone.

Plain-language guide to PMID 27871765 (2017): observational study of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in 23 children.

Key Facts

PMID
27871765
Journal
Medicina clinica
Year
2017
Study type
Observational Study
Authors
Aurensanz Clemente E et al. (5 authors)
DOI
10.1016/j.medcli.2016.09.042

What This Study Did, in Plain Language

What Was Tested

Researchers studied Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in this observational study publication.

Their objective is to evaluate the cardiac morphology and function of SGA children treated with growth hormone (GH), identifying changes that could potentially have long-term consequences.

Who Took Part

The study group was 23 children.

By PubMed's age tags, the people studied were children and teenagers, both men and women.

The researchers selected 23 SGA school-age patients and 23 healthy children.

How the Study Was Run

The researchers measured their weight, height, blood pressure and heart rate.

Using transthoracic echocardiography, the researchers evaluated cardiac chamber size, ascending and abdominal aortic diameter as well as the systolic and diastolic function of both ventricles.

What Was Measured

Topics PubMed links to this paper include Case-Control Studies, Echocardiography, Growth Disorders, Growth Hormone, Heart, Heart Diseases and Infant, Small for Gestational Age.

Author keywords: Ecocardiografía, Estructura, Hormonas, Hormones, Pediatrics and Pediatría.

What This Means in Plain Language

This is an observational study of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in 23 children.

With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.

The abstract goes on to report its results in about 6 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2017 (Medicina clinica), a journal based in Spain.

More context: the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) compound page, all human trials.

Our Notes on the Compound

Exogenous HGH, sermorelin & older GHRPs (why they're passed over): Constant levels suppress the body's own GHRH, raise somatostatin and dull pituitary response.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.