The Effect of Pregabalin and Methylcobalamin Combination on the Chronic Postthoracotomy Pain Syndrome

What Was Tested

This randomized controlled trial paper looks at Cyanocobalamin (Vitamin B12) in the context of chronic pain: fibromyalgia & crps.

Chronic postthoracotomy pain (CPTP) consists of different types of pain.

Some characteristics of CPTP are the same as those of recognized neuropathic pain syndromes.

Who Took Part

The abstract describes 50 patients taking part.

By PubMed's age tags, the people studied were adults, middle-aged adults and older adults, both men and women.

One hundred consecutive patients with CPTP after posterolateral/lateral thoracotomy were prospectively randomly assigned and evaluated.

Fifty patients were given PG-B12 and another 50 patients were given DP treatment.

How the Study Was Run

The design is described as randomized.

The patients were allocated by chance, so the Cyanocobalamin (Vitamin B12) group and the comparison group should start out alike.

Visual Analogue Scale (VAS) and the Leeds Assessment of Neuropathic Symptoms and Signs (LANSS) scorings were performed previous to the treatment (day 0) and on the 15th, 30th, 60th, and 90th days.

What Was Measured

PubMed files the paper under topics including Analgesics, Anti-Inflammatory Agents, Non-Steroidal, Chronic Pain, Diclofenac, Drug Combinations, Pain Measurement and Postoperative Pain.

What This Means in Plain Language

The paper is a randomized study of Cyanocobalamin (Vitamin B12) in 50 patients in people with chronic pain: fibromyalgia & crps.

Results are reported in around 6 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2017 (The Annals of thoracic surgery), a journal based in Netherlands.

More context: the Cyanocobalamin (Vitamin B12) compound page, Chronic pain: fibromyalgia & CRPS research.