← Human Trials & Peer-Reviewed Studies

The effects of a multi-ingredient supplement on markers of muscle damage and inflammation following downhill running in females.

Plain-language guide to PMID 27924138 (2016): double-blind randomized controlled trial of Copper (Supplement).

Key Facts

PMID
27924138
Journal
Journal of the International Society of Sports Nutrition
Year
2016
Study type
Randomized Controlled Trial
Authors
Köhne JL et al. (3 authors)
DOI
10.1186/s12970-016-0156-5

What This Study Did, in Plain Language

What Was Tested

This randomized controlled trial looks at Copper (Supplement).

The purpose of this study was to determine the impact of MIPS (NO-Shotgun®) pre-loaded 4 weeks prior to a single-bout of downhill running (DHR) on hsC-Reactive Protein (hsCRP), interleukin (IL)-6, creatine kinase (CK), muscle soreness, lower limb circumferences and performance.

Why It Was Studied

The effects of a multi-ingredient performance supplement (MIPS) on markers of inflammation and muscle damage, perceived soreness and lower limb performance are unknown in endurance-trained female athletes.

Who Took Part

By PubMed's age tags, the people studied were adults, women only.

How the Study Was Run

The researchers set it up as a randomized, double-blind and placebo-controlled study.

The participants were allocated by chance, so the Copper (Supplement) group and the comparison group should start out alike.

Neither the participants nor the staff measuring them knew who was on Copper (Supplement), so expectations could not easily colour the readings.

A placebo (an inactive look-alike) gave the Copper (Supplement) group a baseline to be compared against.

What Was Measured

Topics PubMed links to this paper include Athletes, Biomarkers, Creatine Kinase, Dietary Supplements, Inflammation, Interleukin-6 and Myalgia.

The authors tagged it with the keywords Eccentric exercise, Muscle soreness and Recovery.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Copper (Supplement).

The abstract goes on to report its results in about 6 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2016 (Journal of the International Society of Sports Nutrition), a journal based in United States.

More context: the Copper (Supplement) compound page, all human trials.

Our Notes on the Compound

Copper (Supplement): The active site of cytochrome c oxidase is described as containing copper ions that are essential for electron transfer.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.