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The effect of vitamin D supplementation on pain, quality of life, and nerve conduction studies in women with chronic widespread pain.

Plain-language guide to PMID 28030514 (2017): open-label clinical trial of Vitamin D, K2, Magnesium and Zinc, chronic pain: fibromyalgia & crps.

Key Facts

PMID
28030514
Journal
International journal of rehabilitation research. Internationale Zeitschrift fur Rehabilitationsforschung. Revue internationale de recherches de readaptation
Year
2017
Study type
Clinical Trial
Authors
Akyuz G et al. (5 authors)
DOI
10.1097/MRR.0000000000000211

What This Study Did, in Plain Language

What Was Tested

The paper reports a study of Vitamin D, K2, Magnesium and Zinc in the context of chronic pain: fibromyalgia & crps, published as a clinical trial.

The aim of this study was to investigate the effects of vitamin D supplementation on pain, quality of life, and nerve conduction studies (NCSs) in women with chronic widespread pain (CWP) diagnosed with Vitamin D insufficiency.

Why It Was Studied

The P-value was adjusted to account for the number of comparisons performed in each assessment.

Who Took Part

PubMed indexes the participants as teenagers, young adults and adults, women only.

Thirty-three female participants with CWP and vitamin D insufficiency were included in this open-label trial.

They were evaluated by routine NCSs in upper and lower limbs, pain scales, and the Nottingham Health Profile before and 8 weeks after starting vitamin D supplementation therapy.

How the Study Was Run

The design is described as open-label.

Everyone knew when Vitamin D, K2, Magnesium and Zinc was being given (open label), which is simpler to run but leaves more room for expectations to affect what is reported.

What Was Measured

The P-value was adjusted to account for the number of comparisons performed in each assessment.

PubMed files the paper under topics including Chronic Pain, Dietary Supplements, Neural Conduction, Quality of Life, Visual Analog Scale, Vitamin D and Vitamin D Deficiency.

What This Means in Plain Language

The paper is an open-label study of Vitamin D, K2, Magnesium and Zinc in people with chronic pain: fibromyalgia & crps.

The publication is from 2017 (International journal of rehabilitation research. Internationale Zeitschrift fur Rehabilitationsforschung. Revue internationale de recherches de readaptation), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, Chronic pain: fibromyalgia & CRPS research.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.