Dietary epigallocatechin 3-gallate supplement improves maternal and neonatal treatment outcome of gestational diabetes mellitus: a double-blind randomised controlled trial.

What Was Tested

This randomized controlled trial looks at Copper (Supplement).

Who Took Part

According to the abstract, 472 women were involved.

By PubMed's age tags, the people studied were infants and adults, women only.

In total, 472 pregnant women during their third trimester of pregnancy were diagnosed with GDM and subsequently enrolled into this trial.

How the Study Was Run

The researchers set it up as a randomized, double-blind and placebo-controlled study.

Random assignment meant chance, not the researchers, decided who got Copper (Supplement) and who got the comparison, which limits bias.

Neither the women nor the staff measuring them knew who was on Copper (Supplement), so expectations could not easily colour the readings.

A placebo (an inactive look-alike) gave the Copper (Supplement) group a baseline to be compared against.

Maternal diabetic parameters at baseline and full term, including metabolism of glucose and insulin, as well as neonatal symptoms at birth, including birth weight, macrosomia, hypoglycaemia, respiratory distress and Apgar scores, were analysed.

What Was Measured

PubMed files the paper under topics including Anthropometry, Blood Glucose, Catechin, Diabetes, Gestational, Dietary Supplements, Fetal Macrosomia and Hypoglycemia.

Author keywords: epigallocatechin 3-gallate, gestational diabetes mellitus, hypoglycaemia and insulin.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Copper (Supplement) in 472 women.

With several hundred people or more, it is a fairly large study for this kind of research.

The abstract goes on to report its results in about 3 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2017 (Journal of human nutrition and dietetics : the official journal of the British Dietetic Association), a journal based in England.

More context: the Copper (Supplement) compound page, all human trials.