Impact of 3-Monthly Vitamin D Supplementation Plus Exercise on Survival after Surgery for Osteoporotic Hip Fracture in Adult Patients over 50 Years: A Pragmatic Randomized, Partially Blinded, Controlled Trial.

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc in this randomized controlled trial publication.

Who Took Part

The study group was 675 patients.

The age groups tagged for this paper are middle-aged adults, older adults and people over 80, both men and women.

Patients admitted to a tertiary university hospital for acute hip fracture.

675 healthy adult patients undergoing surgery for osteoporotic hip fracture were recruited from January 2004 to December 2007.

How the Study Was Run

In design terms this was a randomized, single-blind and placebo-controlled study.

Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

In this single-blind Vitamin D, K2, Magnesium and Zinc study one party knew the assignments and the other did not.

The comparison arm used a placebo, so changes seen with Vitamin D, K2, Magnesium and Zinc could be set against what happens without it.

A pragmatic, randomized, partially single-blind placebo-controlled study.

Patients who received calcifediol were also given an exercise programme.

The placebo group received standard health recommendations only.

The primary endpoint was survival at 1 year and at 4 year follow-up.

The researchers also recorded new fractures, medical complications and anti-osteoporotic treatment compliance.

What Was Measured

The subject headings attached to it are Calcifediol, Dietary Supplements, Exercise, Hip Fractures, Osteoporotic Fractures, Patient Compliance and Spain.

Author keywords: Vitamin D, osteoporosis and survival.

What This Means in Plain Language

The paper is a randomized, single-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc in 675 patients.

With several hundred people or more, it is a fairly large study for this kind of research.

Its findings take up roughly 9 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2017 (The journal of nutrition, health & aging), a journal based in France.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.