Magnesium sulfate for neuroprotection in the setting of chorioamnionitis.

What Was Tested

This randomized controlled trial looks at Vitamin D, K2, Magnesium and Zinc.

The researchers examined the effects of magnesium on premature neonatal outcomes complicated by chorioamnionitis.

Who Took Part

The age groups tagged for this paper are adults, women only.

Outcomes examined include CP, IVH, NEC, BPD, and assessments of mental and motor disability.

How the Study Was Run

In design terms this was a randomized study.

Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

The researchers compared the effect of magnesium sulfate by the presence or absence of chorioamnionitis.

What Was Measured

The subject headings attached to it are Cerebral Palsy, Chorioamnionitis, Magnesium Sulfate, Neuroprotective Agents, Pregnancy Outcome, Premature Birth and Prenatal Care.

The authors tagged it with the keywords neuroprotection and preterm birth.

What This Means in Plain Language

The paper is a randomized study of Vitamin D, K2, Magnesium and Zinc.

Results are reported in around 4 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2018 (The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.