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Clinical Evaluation of a Polyherbal Nutritional Supplement in Dyslipidemic Volunteers.
Plain-language guide to PMID 28406728 (2017): clinical trial of Copper (Supplement).
Key Facts
- PMID
- 28406728
- Journal
- Journal of dietary supplements
- Year
- 2017
- Study type
- Clinical Trial
- Authors
- Suganya S et al. (7 authors)
- DOI
- 10.1080/19390211.2017.1305478
What This Study Did, in Plain Language
What Was Tested
This clinical trial looks at Copper (Supplement).
The aim of the study was to characterize the biochemical properties of the polyherbal formulation (nutritional supplement) and evaluate its use to control dyslipidemia in patients.
Investigation in human volunteers was conducted to evaluate the effect on dyslipidemia as measured by serum lipid biomarkers.
Biomarker values at baseline and at 6th visit (end of review, 8/9 months) were compared to assess the usefulness of the nutritional supplement in the normalization of lipid biomarkers.
Why It Was Studied
Ten important plant parts routinely used in South Indian ethnic food preparation as spices and condiments were investigated for their potential antidyslipidemic properties.
Phytochemical evaluation, in vitro α-amylase inhibitory assay, and high performance thin layer chromatography (HPTLC) fingerprinting were carried out with alcoholic extracts of all 10 individual plants and with the nutritional supplement.
Who Took Part
By PubMed's age tags, the people studied were teenagers, young adults, adults and middle-aged adults, both men and women.
Sixty-five volunteers were recruited for this study.
What Was Measured
Phytochemical evaluation, in vitro α-amylase inhibitory assay, and high performance thin layer chromatography (HPTLC) fingerprinting were carried out with alcoholic extracts of all 10 individual plants and with the nutritional supplement.
In the qualitative analysis of metabolites, the results revealed the presence of various bioactive primary and secondary metabolites that might be responsible for their medicinal attributes.
The subject headings attached to it are Biomarkers, Blood Glucose, Case-Control Studies, Cholesterol, Chromatography, High Pressure Liquid, Dietary Supplements and Dyslipidemias.
The authors tagged it with the keywords HPTLC, nutritional supplement, patients and polyherbal formulation.
What This Means in Plain Language
This is a clinical trial of Copper (Supplement).
The publication is from 2017 (Journal of dietary supplements), a journal based in England.
More context: the Copper (Supplement) compound page, all human trials.
Our Notes on the Compound
Copper (Supplement): The active site of cytochrome c oxidase is described as containing copper ions that are essential for electron transfer.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.