← Human Trials & Peer-Reviewed Studies
The effect of vitamin D supplement on the score and quality of sleep in 20-50 year-old people with sleep disorders compared with control group.
Plain-language guide to PMID 28475473 (2018): double-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc and Copper (Supplement) in 2016 people.
Key Facts
- PMID
- 28475473
- Journal
- Nutritional neuroscience
- Year
- 2018
- Study type
- Randomized Controlled Trial
- Authors
- Majid MS et al. (5 authors)
- DOI
- 10.1080/1028415X.2017.1317395
What This Study Did, in Plain Language
What Was Tested
The paper reports a study of Vitamin D, K2, Magnesium and Zinc and Copper (Supplement), published as a randomized controlled trial.
Sleep quality may be directly related with vitamin D serum level.
Consequently, this study aimed at determining the effect of vitamin D supplements on sleep score and quality in 20-50 year-old people with sleep disorders.
Who Took Part
The study group was 2016 people.
The age groups tagged for this paper are young adults, adults and middle-aged adults, both men and women.
Patient samples were divided randomly into two groups: intervention and placebo.
At the end of the study, the data on 89 subjects (44 in intervention group and 45 people in placebo group) were examined.
How the Study Was Run
In design terms this was a randomized, double-blind and placebo-controlled study.
Random assignment meant chance, not the researchers, decided who got Vitamin D, K2, Magnesium and Zinc and who got the comparison, which limits bias.
As a double-blind Vitamin D, K2, Magnesium and Zinc study, the assignments were hidden from both participants and investigators until the end.
Some people received a placebo instead of Vitamin D, K2, Magnesium and Zinc, giving a reference point.
This double blind, clinical trial was performed in November 2015-February 2016 on 89 people with sleep disorders based on Petersburg's Sleep Index.
Meanwhile, placebo group received placebo.
Before and after intervention, Petersburg's Sleep Quality Questionnaire, International Physical Activity Questionnaire, general information questionnaire, sun exposure, vitamin D serum level and 3-day food record questionnaire were assessed and recorded for all participants.
To analyze data, t-test, chi square, ANCOVA, U-Mann-Whitney and Wilcoxon statistical tests were used.
What Was Measured
The subject headings attached to it are Anthropometry, Dietary Supplements, Sleep, Sleep Wake Disorders, Socioeconomic Factors, Sunlight and Surveys and Questionnaires.
Author keywords: Serum vitamin D, Sleep disorders and Vitamin D supplement.
What This Means in Plain Language
The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc and Copper (Supplement) in 2016 people.
With several hundred people or more, it is a fairly large study for this kind of research.
Results are reported in around 3 sentences of the abstract; we leave them to the paper itself rather than summarise them.
The publication is from 2018 (Nutritional neuroscience), a journal based in England.
More context: the Vitamin D, K2, Magnesium and Zinc compound page and the Copper (Supplement) compound page, all human trials.
Our Notes on the Compounds
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Copper (Supplement): The active site of cytochrome c oxidase is described as containing copper ions that are essential for electron transfer.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.