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Vitamin D supplementation and growth in urban Mongol school children: Results from two randomized clinical trials.
Plain-language guide to PMID 28481882 (2017): double-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc in 113 children.
Key Facts
- PMID
- 28481882
- Journal
- PloS one
- Year
- 2017
- Study type
- Randomized Controlled Trial
- Authors
- Ganmaa D et al. (10 authors)
- DOI
- 10.1371/journal.pone.0175237
What This Study Did, in Plain Language
What Was Tested
This randomized controlled trial looks at Vitamin D, K2, Magnesium and Zinc.
The researchers tested the impact of vitamin D-supplementation on serum concentrations of 25-hydroxyvitamin D [25(OH)D] and short-term growth in Mongol children, with very low serum vitamin D levels in winter.
Why It Was Studied
It is unknown whether vitamin D repletion in children with asymptomatic serum vitamin D deficiency can restore normal growth.
Who Took Part
The abstract describes 113 children taking part.
The age groups tagged for this paper are children and teenagers, both men and women.
The researchers conducted two randomized, double-blind, placebo-controlled trials in urban school age children without clinical signs of rickets.
How the Study Was Run
The design is described as randomized, double-blind and placebo-controlled.
The children were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.
Blinding on both sides kept the children and researchers unaware of who received Vitamin D, K2, Magnesium and Zinc.
Some children received a placebo instead of Vitamin D, K2, Magnesium and Zinc, giving a reference point.
What Was Measured
Topics PubMed links to this paper include Growth, Mongolia, Urban Population and Vitamin D.
What This Means in Plain Language
The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc in 113 children.
The abstract goes on to report its results in about 7 sentences; this page does not restate them, so read the paper for the findings and their limits.
The publication is from 2017 (PloS one), a journal based in United States.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.