Effect of magnesium on arrhythmia incidence in patients undergoing coronary artery bypass grafting.

What Was Tested

This randomized controlled trial looks at Vitamin D, K2, Magnesium and Zinc.

Cardiac arrhythmia after coronary artery bypass grafting (CABG) surgery is a common complication of cardiac surgery.

This study evaluates the therapeutic effects of magnesium in cardiac arrhythmia after CABG surgery.

Who Took Part

According to the abstract, 250 patients were involved.

By PubMed's age tags, the people studied were middle-aged adults and older adults, men only.

The clinical trial enrolled 250 patients who underwent CABG.

Based on the initial serum levels of magnesium, patients were divided into two groups: hypomagnesium and normomagnesium.

How the Study Was Run

The researchers set it up as a randomized and placebo-controlled study.

Random assignment meant chance, not the researchers, decided who got Vitamin D, K2, Magnesium and Zinc and who got the comparison, which limits bias.

A placebo (an inactive look-alike) gave the Vitamin D, K2, Magnesium and Zinc group a baseline to be compared against.

Based on bioethics committee requirements, patients in the hypo-magnesium group received magnesium treatments until they attained normal magnesium blood levels.

Both groups underwent CABG with normal blood levels of magnesium.

Data from all four subgroups were analysed statistically and interpreted.

What Was Measured

This study evaluates the therapeutic effects of magnesium in cardiac arrhythmia after CABG surgery.

PubMed files the paper under topics including Arrhythmias, Cardiac, Coronary Artery Bypass, Coronary Artery Disease, Incidence, Magnesium, Magnesium Sulfate and Postoperative Complications.

The authors tagged it with the keywords coronary artery bypass grafting, hypomagnesaemia and magnesium sulphate.

What This Means in Plain Language

The paper is a randomized and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc in 250 patients.

Its findings take up roughly 4 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2018 (ANZ journal of surgery), a journal based in Australia.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.