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Maternal Obesity, 25-Hydroxy Vitamin D Concentration, and Bone Density in Breastfeeding Dyads.

Plain-language guide to PMID 28549637 (2017): double-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc.

Key Facts

PMID
28549637
Journal
The Journal of pediatrics
Year
2017
Study type
Randomized Controlled Trial
Authors
Sen S et al. (4 authors)
DOI
10.1016/j.jpeds.2017.04.024
Registered trial
NCT00412074

What This Study Did, in Plain Language

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc in this randomized controlled trial publication.

To examine the association between maternal body mass index (BMI) and serum 25-hydroxy vitamin D [25(OH)D] concentration and bone density in mother-infant pairs.

Who Took Part

PubMed indexes the participants as infants and adults, women only.

The study was a secondary analysis of 234 exclusively breastfeeding dyads who were recruited in the first postpartum month for a randomized controlled trial of maternal vs infant vitamin D supplementation.

How the Study Was Run

The researchers set it up as a randomized and double-blind study.

Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

Neither the participants nor the staff measuring them knew who was on Vitamin D, K2, Magnesium and Zinc, so expectations could not easily colour the readings.

Mean 25(OH)D concentrations and bone mineral density (BMD) were compared by BMI group.

The adjusted association between maternal BMI and 25(OH)D and bone density was examined at 1, 4, and 7 months postpartum.

What Was Measured

PubMed files the paper under topics including Body Mass Index, Bone Density, Breast Feeding, Dietary Supplements, Maternal Nutritional Physiological Phenomena, Mothers and Obesity.

Author keywords: bone mineralization, breastfeeding, maternal obesity and vitamin D.

What This Means in Plain Language

The paper is a randomized and double-blind study of Vitamin D, K2, Magnesium and Zinc.

Its findings take up roughly 6 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2017 (The Journal of pediatrics), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.