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Effects of Laparoscopic Sleeve Gastrectomy on Parathyroid Hormone, Vitamin D, Calcium, Phosphorus, and Albumin Levels

Plain-language guide to PMID 28569356 (2017): clinical trial study of Parathyroid Hormone (PTH 1-84).

Key Facts

PMID
28569356
Journal
Obesity surgery
Year
2017
Study type
Clinical Trial
Authors
Mihmanli M et al. (8 authors)
DOI
10.1007/s11695-017-2747-x

What This Study Did, in Plain Language

What Was Tested

The paper reports a study of Parathyroid Hormone (PTH 1-84), published as a clinical trial.

The aim of this study was to identify the effects of LSG on iPTH, vitD, calcium (Ca), phosphorus (P), alkaline phosphatase (ALP), and albumin levels.

Why It Was Studied

Endocrinological abnormalities may occur as undesired side effects.

Most centers routinely prescribe folic acid, cyanocobalamin (vitB12), and protein replacement in the postoperative period, but 25-OH-vitamin-D3 (vitD) and intact parathyroid hormone (iPTH) levels are not routinely followed up.

Who Took Part

By PubMed's age tags, the people studied were teenagers, young adults, adults, middle-aged adults and older adults, both men and women.

How the Study Was Run

Serum levels of iPTH, vitD, Ca, P, folic acid, vitB12, ALP, and albumin were measured preoperatively and postoperatively at the 3rd, 6th, and 12th months.

What Was Measured

Most centers routinely prescribe folic acid, cyanocobalamin (vitB12), and protein replacement in the postoperative period, but 25-OH-vitamin-D3 (vitD) and intact parathyroid hormone (iPTH) levels are not routinely followed up.

PubMed files the paper under topics including Albumins, Calcium, Dietary Supplements, Gastrectomy, Laparoscopy, Malabsorption Syndromes and Metabolic Diseases.

Author keywords: Alkaline phosphatase, Metabolic disorders, Morbid obesity, Sleeve gastrectomy and Vitamin D.

What This Means in Plain Language

This is a clinical trial of Parathyroid Hormone (PTH 1-84).

Its findings take up roughly 9 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2017 (Obesity surgery), a journal based in United States.

More context: the Parathyroid Hormone (PTH 1-84) compound page, all human trials.

Our Notes on the Compound

Parathyroid Hormone (PTH 1-84): The 84-amino-acid hormone that raises blood calcium; full-length PTH (Natpara) has been used in hypoparathyroidism. Teriparatide is its 1-34 fragment.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.