Effects of high-dose parenteral vitamin D therapy on lipid profile and blood pressure in patients with diabetic nephropathy: A randomized double-blind clinical trial.

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc in the context of low blood pressure and orthostatic hypotension in this randomized controlled trial publication.

Selected patients were allocated to two groups by Block randomization method.

Blood and urine were collected at the baseline for biochemical analyses and blood pressure was measured.

Who Took Part

The age groups tagged for this paper are middle-aged adults, both men and women.

How the Study Was Run

In design terms this was a randomized and double-blind study.

Random assignment meant chance, not the researchers, decided who got Vitamin D, K2, Magnesium and Zinc and who got the comparison, which limits bias.

As a double-blind Vitamin D, K2, Magnesium and Zinc study, the assignments were hidden from both participants and investigators until the end.

What Was Measured

Topics PubMed links to this paper include Biomarkers, Blood Pressure Determination, Case-Control Studies, Cholesterol, HDL, Cholesterol, LDL, Diabetes Mellitus, Type 2 and Diabetic Nephropathies.

Author keywords: Clinical trial, Lipoproteins and Vitamin D.

What This Means in Plain Language

The paper is a randomized and double-blind study of Vitamin D, K2, Magnesium and Zinc in people with low blood pressure and orthostatic hypotension.

Its findings take up roughly 5 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2017 (Diabetes & metabolic syndrome), a journal based in Netherlands.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, Low blood pressure and orthostatic hypotension research.