Dietary habits; concentration of copper, zinc, and Cu-to-Zn ratio in serum and ability status of patients with relapsing-remitting multiple sclerosis.

Plain-language guide to PMID 28606574 (2017): observational study of Vitamin D, K2, Magnesium and Zinc and Copper (Supplement) in 101 individuals, multiple sclerosis.

Key Facts

PMID: 28606574
Journal: Nutrition (Burbank, Los Angeles County, Calif.)
Year: 2017
Study type: Observational Study
Authors: Socha K et al. (8 authors)
DOI: 10.1016/j.nut.2017.03.009

What This Study Did, in Plain Language

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc and Copper (Supplement) in the context of multiple sclerosis in this observational study publication.

Dietary habits and adequate intake of antioxidants in the diet-for example, copper (Cu) and zinc (Zn)-may be an environmental factor in the occurrence of multiple sclerosis (MS).

The aim of this study was to estimate the influence of dietary habits on the concentration of Cu, Zn in the serum, and the effect of Cu-to-Zn ratio on the ability status of patients with relapsing-remitting MS.

Who Took Part

According to the abstract, 101 individuals were involved.

PubMed indexes the participants as teenagers, young adults, adults, middle-aged adults and older adults, both men and women.

This was an observational case-control study that included 101 individuals with MS and 68 healthy individuals (controls).

The ratio of Cu to Zn was calculated and compared with the Expanded Disability Status Scale of patients.

How the Study Was Run

Food frequency questionnaires were used to collect dietary data.

Serum concentrations of Cu and Zn were determined by the electrothermal and flame atomic absorption spectrometry method, respectively.

What Was Measured

The subject headings attached to it are Case-Control Studies, Copper, Diet, Feeding Behavior, Multiple Sclerosis, Spectrophotometry, Atomic and Zinc.

Author keywords: Ability status, Cu-to-Zn ratio and Dietary habits.

What This Means in Plain Language

This is an observational study of Vitamin D, K2, Magnesium and Zinc and Copper (Supplement) in 101 individuals in people with multiple sclerosis.

Results are reported in around 6 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2017 (Nutrition (Burbank, Los Angeles County, Calif.)), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page and the Copper (Supplement) compound page, Multiple sclerosis research.

Our Notes on the Compounds

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Copper (Supplement): The active site of cytochrome c oxidase is described as containing copper ions that are essential for electron transfer.

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.