[Evaluation of the effects of a natural dietary supplement with cranberry, Noxamicina® and D-mannose in recurrent urinary infections in perimenopausal women].

What Was Tested

This randomized controlled trial looks at Copper (Supplement).

The female genital apparatus, the urinary tract and the perineal supporting tissues share a common embryological origin, whose differentiation depends on the action of estrogens.

With a view to verifying whether the use of a new dietary supplement (Kistinox® Forte sachets) containing cranberry (Vaccinium macrocarpon), Noxamicina® (propolis extract) and D-mannose can be of use in the treatment of cystitis, with or without bacteriuria, through the elimination of urinary symptoms, a multicenter clinical study was conducted on 150 women aged 40 to 50 suffering from recurrent episodes of cystitis as attested by at least one positive urine culture during the six months preceding their recruitment.

Who Took Part

The abstract describes 150 women taking part.

By PubMed's age tags, the people studied were adults and middle-aged adults, women only.

How the Study Was Run

The design is described as randomized and multicenter.

Because people in this Copper (Supplement) study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

More than one site took part, so the women came from several places.

What Was Measured

With a view to verifying whether the use of a new dietary supplement (Kistinox® Forte sachets) containing cranberry (Vaccinium macrocarpon), Noxamicina® (propolis extract) and D-mannose can be of use in the treatment of cystitis, with or without bacteriuria, through the elimination of urinary symptoms, a multicenter clinical study was conducted on 150 women aged 40 to 50 suffering from recurrent episodes of cystitis as attested by at least one positive urine culture during the six months preceding their recruitment.

Topics PubMed links to this paper include Cystitis, Dietary Supplements, Mannose, Perimenopause, Plant Extracts, Quality of Life and Urinary Tract Infections.

What This Means in Plain Language

The paper is a randomized and multicenter study of Copper (Supplement) in 150 women.

Results are reported in around 3 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2017 (Minerva ginecologica), a journal based in Italy.

More context: the Copper (Supplement) compound page, all human trials.