Racial/ethnic disparities in magnesium sulfate neuroprotection: a subgroup analysis of a multicenter randomized controlled trial.

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc in this randomized controlled trial publication.

The researchers analyze the effect of race/ethnicity in maternal/infant outcomes after MgSO4 neuroprotection.

Who Took Part

The age groups tagged for this paper are young adults and adults, women only.

Subgroup analysis of a multicenter clinical trial (BEAM trial) where pregnant women at risk of preterm birth were randomized to either MgSO4 or placebo.

How the Study Was Run

The researchers set it up as a randomized, placebo-controlled and multicenter study.

Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

The comparison arm used a placebo, so changes seen with Vitamin D, K2, Magnesium and Zinc could be set against what happens without it.

Running at several centres spread the Vitamin D, K2, Magnesium and Zinc study over different clinics and patient groups.

The effect of race in maternal/neonatal outcomes after MgSO4 was analyzed with Breslow-Day and multifactorial ANOVA.

What Was Measured

Topics PubMed links to this paper include Drug-Related Side Effects and Adverse Reactions, Ethnicity, Magnesium Sulfate, Neuroprotection, Pregnancy Outcome, Premature Birth and Racial Groups.

Author keywords: Adverse effects, continental population groups, ethnic groups and pregnancy complications.

What This Means in Plain Language

The paper is a randomized, placebo-controlled and multicenter study of Vitamin D, K2, Magnesium and Zinc.

Its findings take up roughly 5 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2018 (The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.