Oral Consumption of Vitamin K2 for 8 Weeks Associated With Increased Maximal Cardiac Output During Exercise

What Was Tested

This randomized controlled trial paper looks at Vitamin D, K2, Magnesium and Zinc.

Objective • The purpose of this study was to determine if 8 wk of dietary supplementation with Vitamin K2 could alter cardiovascular responses to a graded cycle ergometer test.

Why It Was Studied

Background • Vitamin K1 and K2 are not typically common in a Western diet because they are found in a variety of fermented foods.

Design • The study was a randomized controlled trial.

Who Took Part

The abstract describes 4, participants taking part.

PubMed indexes the participants as young adults, both men and women.

How the Study Was Run

The design is described as randomized and placebo-controlled.

Random assignment meant chance, not the researchers, decided who got Vitamin D, K2, Magnesium and Zinc and who got the comparison, which limits bias.

The comparison arm used a placebo, so changes seen with Vitamin D, K2, Magnesium and Zinc could be set against what happens without it.

What Was Measured

Topics PubMed links to this paper include Area Under Curve, Cardiac Output, Dietary Supplements, Exercise, Exercise Test, Heart Rate and Oxygen Consumption.

What This Means in Plain Language

The paper is a randomized and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc in 4, participants.

With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.

The publication is from 2017 (Alternative therapies in health and medicine), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.