No Severe Hypercalcemia with Daily Vitamin D3 Supplementation of up to during the First Year of Life.

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc and Parathyroid Hormone (PTH 1-84) in this randomized controlled trial publication.

High intake may result in hypercalcemia.

Who Took Part

The study group was 987 children.

The age groups tagged for this paper are infants, both men and women.

How the Study Was Run

The researchers set it up as a randomized and double-blind study.

The children were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.

Blinding on both sides kept the children and researchers unaware of who received Vitamin D, K2, Magnesium and Zinc.

Ionized calcium (Ca-ion) was analyzed at 6 and 12 months, and serum 25-hydroxyvitamin D (25-OHD) and parathyroid hormone (PTH) concentration at 12 months.

What Was Measured

The subject headings attached to it are Calcium, Cholecalciferol, Dietary Supplements, Hypercalcemia, Incidence, Prevalence and Rickets.

Author keywords: 25-Hydroxyvitamin D, Calcium and phosphate metabolism, Infancy, Ionized calcium, Parathyroid hormone and Vitamin D.

What This Means in Plain Language

The paper is a randomized and double-blind study of Vitamin D, K2, Magnesium and Zinc and Parathyroid Hormone (PTH 1-84) in 987 children.

With several hundred people or more, it is a fairly large study for this kind of research.

Its findings take up roughly 4 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2017 (Hormone research in paediatrics), a journal based in Switzerland.

More context: the Vitamin D, K2, Magnesium and Zinc compound page and the Parathyroid Hormone (PTH 1-84) compound page, all human trials.