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Duphaston and human menopausal gonadotropin protocol in normally ovulatory women undergoing controlled ovarian hyperstimulation during in vitro fertilization/intracytoplasmic sperm injection treatments in combination with embryo cryopreservation
Plain-language guide to PMID 28697910 (2017): randomized controlled trial study of HMG (Human Menopausal Gonadotropin) in 250 patients.
Key Facts
- PMID
- 28697910
- Journal
- Fertility and sterility
- Year
- 2017
- Study type
- Randomized Controlled Trial
- Authors
- Zhu X et al. (3 authors)
- DOI
- 10.1016/j.fertnstert.2017.06.017
What This Study Did, in Plain Language
What Was Tested
Researchers studied HMG (Human Menopausal Gonadotropin) in this randomized controlled trial publication.
To evaluate endocrine characteristics and clinical outcomes in normal ovulatory patients undergoing controlled ovarian hyperstimulation (COH) with the use of a Duphaston and hMG protocol during in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI) treatments in combination with frozen-thawed embryo transfer (FET) compared with the characteristics and outcomes of patients undergoing an Utrogestan and hMG protocol.
Who Took Part
The study group was 250 patients.
PubMed indexes the participants as young adults and adults, women only.
A total of 250 infertile patients undergoing IVF/ICSI treatments.
How the Study Was Run
In design terms this was a randomized study.
Because people in this HMG (Human Menopausal Gonadotropin) study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.
Tertiary care academic medical center.
Viable embryos were cryopreserved in both protocols for transfer at a later time.
What Was Measured
The subject headings attached to it are China, Combined Modality Therapy, Cryopreservation, Dydrogesterone, Fertilization in Vitro, Infertility and Luteinizing Hormone.
The authors tagged it with the keywords Duphaston, Utrogestan, frozen-thawed embryo transfer, premature LH surge and progesterone protocol.
What This Means in Plain Language
The paper is a randomized study of HMG (Human Menopausal Gonadotropin) in 250 patients.
Its findings take up roughly 8 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.
The publication is from 2017 (Fertility and sterility), a journal based in United States.
More context: the HMG (Human Menopausal Gonadotropin) compound page, all human trials.
Our Notes on the Compound
HMG (Human Menopausal Gonadotropin): Menotropins: a glycoprotein preparation that supplies follicle-stimulating hormone (FSH) and luteinizing hormone (LH) activity.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.