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Effects of a hops (Humulus lupulus L.) dry extract supplement on self-reported depression, anxiety and stress levels in apparently healthy young adults: a randomized, placebo-controlled, double-blind, crossover pilot study.
Plain-language guide to PMID 28742505 (2017): double-blind randomized controlled trial of Copper (Supplement).
Key Facts
- PMID
- 28742505
- Journal
- Hormones (Athens, Greece)
- Year
- 2017
- Study type
- Randomized Controlled Trial
- Authors
- Kyrou I et al. (7 authors)
- DOI
- 10.14310/horm.2002.1738
What This Study Did, in Plain Language
What Was Tested
Researchers studied Copper (Supplement) in this randomized controlled trial publication.
The Humulus lupulus L. plant (hops) is used as a herbal medicinal product for anxiety/mood disorders.
Their aim was to study the effects of a hops dry extract on self-reported depression, anxiety and stress levels in young adults.
Who Took Part
The age groups tagged for this paper are young adults and adults, both men and women.
Apparently healthy young adults from their university completed the Depression Anxiety Stress Scale-21 (DASS-21) and those reporting at least mild depression, anxiety and stress were invited to complete the study intervention.
How the Study Was Run
The researchers set it up as a randomized, double-blind, placebo-controlled and crossover study.
Random assignment meant chance, not the researchers, decided who got Copper (Supplement) and who got the comparison, which limits bias.
As a double-blind Copper (Supplement) study, the assignments were hidden from both participants and investigators until the end.
The comparison arm used a placebo, so changes seen with Copper (Supplement) could be set against what happens without it.
In the crossover set-up each of the participants took both Copper (Supplement) and the comparison in turn, acting as their own control.
What Was Measured
PubMed files the paper under topics including Anxiety, Depression, Humulus, Outcome Assessment, Health Care, Plant Extracts and Stress, Psychological.
What This Means in Plain Language
The paper is a randomized, double-blind and placebo-controlled study of Copper (Supplement).
Its findings take up roughly 5 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.
The publication is from 2017 (Hormones (Athens, Greece)), a journal based in Switzerland.
More context: the Copper (Supplement) compound page, all human trials.
Our Notes on the Compound
Copper (Supplement): The active site of cytochrome c oxidase is described as containing copper ions that are essential for electron transfer.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.