← Human Trials & Peer-Reviewed Studies
The effects of vitamin D supplementation on metabolic profiles and liver function in patients with non-alcoholic fatty liver disease: A systematic review and meta-analysis of randomized controlled trials.
Plain-language guide to PMID 28751149 (2017): meta-analysis of Vitamin D, K2, Magnesium and Zinc and Copper (Supplement), fatty liver & elevated liver enzymes.
Key Facts
- PMID
- 28751149
- Journal
- Diabetes & metabolic syndrome
- Year
- 2017
- Study type
- Meta-Analysis
- Authors
- Tabrizi R et al. (8 authors)
- DOI
- 10.1016/j.dsx.2017.07.025
What This Paper Covers, in Plain Language
What It Covers
Researchers studied Vitamin D, K2, Magnesium and Zinc and Copper (Supplement) in the context of fatty liver & elevated liver enzymes in this meta-analysis publication.
A systematic review and meta-analysis of randomized controlled trials (RCTs) was conducted to summarize the evidence on the effect of vitamin D supplementation on metabolic profiles in patients with non-alcoholic fatty liver disease (NAFLD).
Who the Included Studies Covered
Seven RCTs with 452 participants (227 patients and 225 controls) were included in the meta-analysis.
How the Review Was Done
The researchers systematically searched PubMed, EMBASE and five other databases to identify all RCTs investigating the association between vitamin D and NAFLD up until 5 October 2016.
What Was Measured
The subject headings attached to it are Blood Glucose, Dietary Supplements, Lipids, Liver, Non-alcoholic Fatty Liver Disease and Vitamin D.
The authors tagged it with the keywords Liver function, Meta-analysis, Metabolic profiles and Vitamin D supplement.
What This Means in Plain Language
This is a meta-analysis of Vitamin D, K2, Magnesium and Zinc and Copper (Supplement) in people with fatty liver & elevated liver enzymes.
The abstract goes on to report its results in about 3 sentences; this page does not restate them, so read the paper for the findings and their limits.
The publication is from 2017 (Diabetes & metabolic syndrome), a journal based in Netherlands.
More context: the Vitamin D, K2, Magnesium and Zinc compound page and the Copper (Supplement) compound page, Fatty liver & elevated liver enzymes research.
Our Notes on the Compounds
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Copper (Supplement): The active site of cytochrome c oxidase is described as containing copper ions that are essential for electron transfer.
Related Pages
- Fatty liver & elevated liver enzymes research
- Vitamin D, K2, Magnesium and Zinc in the library
- Copper (Supplement) in the library
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.