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Do anabolic nutritional supplements stimulate human growth hormone secretion in elderly women with heart failure?

Plain-language guide to PMID 28778993 (2017): crossover randomized controlled trial of Exogenous HGH, sermorelin & older GHRPs (why they're passed over).

Key Facts

PMID
28778993
Journal
Physiological reports
Year
2017
Study type
Randomized Controlled Trial
Authors
Smeets ETHC et al. (5 authors)
DOI
10.14814/phy2.13366

What This Study Did, in Plain Language

What Was Tested

This randomized controlled trial looks at Exogenous HGH, sermorelin & older GHRPs (why they're passed over).

Therefore, in this study the researchers aimed to investigate the effect of nutritional supplementation on HGH production in elderly women with heart failure.

Why It Was Studied

Growth hormone treatment has gained attention over the past decade as a treatment for heart failure.

However, studies investigating the effect of amino acid (AA) supplementation show conflicting results.

Who Took Part

PubMed indexes the participants as older adults and people over 80, women only.

How the Study Was Run

The design is described as randomized and crossover.

The participants were allocated by chance, so the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) group and the comparison group should start out alike.

In the crossover set-up each of the participants took both Exogenous HGH, sermorelin & older GHRPs (why they're passed over) and the comparison in turn, acting as their own control.

Plasma HGH concentration was measured before and for 4 h following ingestion of a mixture of protein, carbohydrate, and fat or an AA beverage.

What Was Measured

Topics PubMed links to this paper include Anabolic Agents, Arginine, Dietary Supplements, Heart Failure, Human Growth Hormone and Lysine.

Author keywords: Amino acids.

What This Means in Plain Language

The paper is a randomized and crossover study of Exogenous HGH, sermorelin & older GHRPs (why they're passed over).

The publication is from 2017 (Physiological reports), a journal based in United States.

More context: the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) compound page, all human trials.

Our Notes on the Compound

Exogenous HGH, sermorelin & older GHRPs (why they're passed over): Constant levels suppress the body's own GHRH, raise somatostatin and dull pituitary response.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.