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The effects of a lipid-based nutrient supplement and antiretroviral therapy in a randomized controlled trial on iron, copper, and zinc in milk from HIV-infected Malawian mothers and associations with maternal and infant biomarkers.
Plain-language guide to PMID 28851037 (2018): randomized controlled trial of Vitamin D, K2, Magnesium and Zinc and Copper (Supplement).
Key Facts
- PMID
- 28851037
- Journal
- Maternal & child nutrition
- Year
- 2018
- Study type
- Randomized Controlled Trial
- Authors
- Hampel D et al. (12 authors)
- DOI
- 10.1111/mcn.12503
What This Study Did, in Plain Language
What Was Tested
Researchers studied Vitamin D, K2, Magnesium and Zinc and Copper (Supplement) in this randomized controlled trial publication.
The researchers evaluated effects of antiretroviral (ARV) therapy and lipid-based nutrient supplements (LNSs) on iron, copper, and zinc in milk of exclusively breastfeeding HIV-infected Malawian mothers and their correlations with maternal and infant biomarkers.
Human milk and blood at 2, 6, and 24 weeks post-partum and blood during pregnancy (≤30 weeks gestation) were collected from 535 mothers/infant-pairs in the Breastfeeding, Antiretrovirals, and Nutrition study.
Who Took Part
The age groups tagged for this paper are infants, young adults and adults, both men and women.
How the Study Was Run
In design terms this was a randomized study.
Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.
What Was Measured
The researchers evaluated effects of antiretroviral (ARV) therapy and lipid-based nutrient supplements (LNSs) on iron, copper, and zinc in milk of exclusively breastfeeding HIV-infected Malawian mothers and their correlations with maternal and infant biomarkers.
Topics PubMed links to this paper include Anti-HIV Agents, Biomarkers, Breast Feeding, Copper, Dietary Supplements, HIV Infections and Hemoglobins.
Author keywords: haemoglobin status, human milk, iron and zinc.
What This Means in Plain Language
The paper is a randomized study of Vitamin D, K2, Magnesium and Zinc and Copper (Supplement).
The publication is from 2018 (Maternal & child nutrition), a journal based in England.
More context: the Vitamin D, K2, Magnesium and Zinc compound page and the Copper (Supplement) compound page, all human trials.
Our Notes on the Compounds
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Copper (Supplement): The active site of cytochrome c oxidase is described as containing copper ions that are essential for electron transfer.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.