Crossover trial to test the acceptability of a locally produced lipid-based nutrient supplement (LNS) for children under 2 years in Cambodia: a study protocol.

What Was Tested

Researchers studied Copper (Supplement) in this randomized controlled trial publication.

In that context, UNICEF and IRD have developed a locally produced, multiple micronutrient fortified lipid-based nutrient supplement.

This food is innovative, in that it uses fish instead of milk as the animal source food.

Who Took Part

By PubMed's age tags, the people studied were infants, both men and women.

The amount they consume will be measured, and at the end of each 3-day set, caregivers will assess how well their child liked the food.

How the Study Was Run

The researchers set it up as a randomized and crossover study.

Random assignment meant chance, not the researchers, decided who got Copper (Supplement) and who got the comparison, which limits bias.

Each person switched between Copper (Supplement) and the comparison at some point, usually with a gap in between.

This is a cluster-randomised, incomplete block, 4×4 crossover design with no blinding.

It will take place in four sites in a community setting in periurban Phnom Penh.

What Was Measured

Very few supplementary foods have non-milk animal source foods, and in addition they have not been widely tested.

This trial will assess the novel food's acceptability to children and caregivers.

The subject headings attached to it are Anthropometry, Cambodia, Child Development, Dietary Fats, Dietary Supplements, Malnutrition and Regression Analysis.

The authors tagged it with the keywords Lipid-based nutrient supplement (LNS), acceptability, hedonic scale, micronutrient powder, ready-to-use supplementary food (RUSF) and test feeding.

What This Means in Plain Language

The paper is a randomized and crossover study of Copper (Supplement).

The publication is from 2017 (BMJ open), a journal based in England.

More context: the Copper (Supplement) compound page, all human trials.