← Human Trials & Peer-Reviewed Studies
[Systematic evaluation on effectiveness and safety of recombinant human growth hormone in treating adult patients with severe burn].
Plain-language guide to PMID 28926879 (2017): review of Exogenous HGH, sermorelin & older GHRPs (why they're passed over).
Key Facts
- PMID
- 28926879
- Journal
- Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns
- Year
- 2017
- Study type
- Review
- Authors
- Tian FY et al. (4 authors)
- DOI
- 10.3760/cma.j.issn.1009-2587.2017.09.009
What This Paper Covers, in Plain Language
What It Covers
The paper reports a study of Exogenous HGH, sermorelin & older GHRPs (why they're passed over), published as a review.
Methods: Databases including PubMed, Cochrane Library, and Embase were searched using key words " burns, thermal, human growth hormone, growth hormone, hGH, and somatropin (human)", and China Biology Medicine disc, Chinese Journals Full-text Database, VIP Database, and Wanfang Database were searched using key words in Chinese version "," to obtain the randomized controlled trials about rhGH in the treatment of adults with severe burn from the establishment of each database to December 2016.
The measurement indexes included hemoglobin (Hb) and plasma total protein, inflammatory factors [including interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α)], incidence rate of sepsis, incidence rate of hyperglycemia, wound healing time, length of stay, and mortality rate.
Who the Included Studies Covered
The age groups tagged for this paper are adults.
Results: A total of 8 trials involving 534 patients were included; 276 patients in rhGH group were treated with rhGH and 258 patients in placebo control group were treated with placebo.
What Was Measured
The measurement indexes included hemoglobin (Hb) and plasma total protein, inflammatory factors [including interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α)], incidence rate of sepsis, incidence rate of hyperglycemia, wound healing time, length of stay, and mortality rate.
Topics PubMed links to this paper include Burns, China, Hemoglobins, Human Growth Hormone, Incidence, Interleukin-6 and Randomized Controlled Trials as Topic.
The authors tagged it with the keywords Systcmatic review.
What This Means in Plain Language
This is a review of Exogenous HGH, sermorelin & older GHRPs (why they're passed over).
The publication is from 2017 (Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns), a journal based in China.
More context: the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) compound page, all human trials.
Our Notes on the Compound
Exogenous HGH, sermorelin & older GHRPs (why they're passed over): Constant levels suppress the body's own GHRH, raise somatostatin and dull pituitary response.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.