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Vitamin D and Testosterone in Healthy Men: A Randomized Controlled Trial.

Plain-language guide to PMID 28938446 (2017): double-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc.

Key Facts

PMID
28938446
Journal
The Journal of clinical endocrinology and metabolism
Year
2017
Study type
Randomized Controlled Trial
Authors
Lerchbaum E et al. (7 authors)
DOI
10.1210/jc.2017-01428
Registered trial
NCT01748370

What This Study Did, in Plain Language

What Was Tested

This randomized controlled trial looks at Vitamin D, K2, Magnesium and Zinc.

Available evidence shows an association of vitamin D with androgen levels in men.

However, results from preliminary randomized controlled trials (RCTs) are conflicting.

Who Took Part

By PubMed's age tags, the people studied were young adults, adults and middle-aged adults, men only.

Endocrine outpatient clinic at the Medical University of Graz, Austria.

How the Study Was Run

The design is described as randomized, double-blind, placebo-controlled and pilot.

Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

Neither the participants nor the staff measuring them knew who was on Vitamin D, K2, Magnesium and Zinc, so expectations could not easily colour the readings.

Some participants received a placebo instead of Vitamin D, K2, Magnesium and Zinc, giving a reference point.

It is described as a pilot, a small early test of whether a larger Vitamin D, K2, Magnesium and Zinc study would be practical.

The Graz Vitamin D&TT-RCT is a single-center, double-blind, randomized, placebo-controlled trial conducted between December 2012 and January 2017.

What Was Measured

Available evidence shows an association of vitamin D with androgen levels in men.

The subject headings attached to it are Dietary Supplements, Health, Pilot Projects, Testosterone, Vitamin D and Vitamin D Deficiency.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc.

The abstract goes on to report its results in about 6 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2017 (The Journal of clinical endocrinology and metabolism), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.