Vitamin K-induced effects on body fat and weight: results from a 3-year vitamin K2 intervention study

What Was Tested

This randomized controlled trial paper looks at Vitamin D, K2, Magnesium and Zinc.

Vitamin K status has been linked to fat and glucose metabolism by several authors, but whether high vitamin K intake influences body weight or composition has remained unclear.

Who Took Part

The abstract describes 214 women taking part.

By PubMed's age tags, the people studied were middle-aged adults and older adults, women only.

How the Study Was Run

The researchers set it up as a randomized, double-blind and placebo-controlled study.

Random assignment meant chance, not the researchers, decided who got Vitamin D, K2, Magnesium and Zinc and who got the comparison, which limits bias.

Blinding on both sides kept the women and researchers unaware of who received Vitamin D, K2, Magnesium and Zinc.

Some women received a placebo instead of Vitamin D, K2, Magnesium and Zinc, giving a reference point.

Osteocalcin (OC) carboxylation was used as a marker for vitamin K status, and fat distribution was assessed by dual-energy X-ray absorptiometry total body scan.

What Was Measured

Topics PubMed links to this paper include Adipose Tissue, Body Composition, Intra-Abdominal Fat, Osteocalcin, Postmenopause, Vitamin K 2 and Waist Circumference.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc in 214 women.

Results are reported in around 5 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2018 (European journal of clinical nutrition), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.