Serum zinc, copper and iron status of children with coeliac disease on three months of gluten-free diet with or without four weeks of zinc supplements: a randomised controlled trial.

What Was Tested

This randomized controlled trial looks at Vitamin D, K2, Magnesium and Zinc and Copper (Supplement).

Data about the effect of zinc supplementation with gluten-free diet on normalisation of plasma zinc, copper and iron in patients with coeliac disease are scanty.

The researchers evaluated the effect of zinc supplementation on serum zinc, copper and iron levels in patients with coeliac disease, by randomising 71 children newly diagnosed with coeliac disease into two groups: Group A = gluten-free diet (GFD); and Group B = gluten-free diet with zinc supplements (GFD +Zn).

Who Took Part

According to the abstract, 71 children were involved.

PubMed indexes the participants as young children, children and teenagers, both men and women.

How the Study Was Run

The researchers set it up as a randomized and crossover study.

Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

Each person switched between Vitamin D, K2, Magnesium and Zinc and the comparison at some point, usually with a gap in between.

What Was Measured

The researchers evaluated the effect of zinc supplementation on serum zinc, copper and iron levels in patients with coeliac disease, by randomising 71 children newly diagnosed with coeliac disease into two groups: Group A = gluten-free diet (GFD); and Group B = gluten-free diet with zinc supplements (GFD +Zn).

The subject headings attached to it are Celiac Disease, Copper, Diet, Gluten-Free, Dietary Supplements, Iron and Zinc.

The authors tagged it with the keywords Asia, digestive, location, physiology and treatment.

What This Means in Plain Language

The paper is a randomized and crossover study of Vitamin D, K2, Magnesium and Zinc and Copper (Supplement) in 71 children.

The publication is from 2018 (Tropical doctor), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page and the Copper (Supplement) compound page, all human trials.