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Efficacy of Magnesium Sulfate Added to Local Anesthetic in a Transversus Abdominis Plane Block for Analgesia Following Total Abdominal Hysterectomy: A Randomized Trial.

Plain-language guide to PMID 29149143 (2017): double-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc in 60 women.

Key Facts

PMID
29149143
Journal
Pain physician
Year
2017
Study type
Randomized Controlled Trial
Authors
Abd-Elsalam KA et al. (6 authors)
Registered trial
NCT02930707

What This Study Did, in Plain Language

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc in this randomized controlled trial publication.

Magnesium sulfate, TAP block, postoperative pain, total abdominal hysterectomy.

Who Took Part

The study group was 60 women.

PubMed indexes the participants as adults and middle-aged adults, women only.

This randomized, double-blinded clinical trial included 60 women undergoing total abdominal hysterectomy that were divided into 2 groups (30 patients per group).

How the Study Was Run

The researchers set it up as a randomized and double-blind study.

Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

As a double-blind Vitamin D, K2, Magnesium and Zinc study, the assignments were hidden from both participants and investigators until the end.

A prospective, randomized, double-blinded clinical trial.

This study is registered at https://clinicaltrials.gov (no.: NCT02930707).

Visual analog scale (VAS) scores, the time of the first analgesic request, total morphine consumption, and any side effects were assessed and recorded.

What Was Measured

The subject headings attached to it are Abdomen, Analgesics, Opioid, Anesthetics, Local, Bupivacaine, Hysterectomy, Magnesium Sulfate and Morphine.

What This Means in Plain Language

The paper is a randomized and double-blind study of Vitamin D, K2, Magnesium and Zinc in 60 women.

Its findings take up roughly 4 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2017 (Pain physician), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.