Efficacy of Acupuncture Is Noninferior to Nicotine Replacement Therapy for Tobacco Cessation: Results of a Prospective, Randomized, Active-Controlled Open-Label Trial.

Plain-language guide to PMID 29175360 (2018): open-label randomized controlled trial of Therapeutic nicotine (patch, non-peptide).

Key Facts

PMID: 29175360
Journal: Chest
Year: 2018
Study type: Randomized Controlled Trial
Authors: Wang YY et al. (7 authors)
DOI: 10.1016/j.chest.2017.11.015

What This Study Did, in Plain Language

What Was Tested

The paper reports a study of Therapeutic nicotine (patch, non-peptide), published as a randomized controlled trial.

Chinese Clinical Trial Registry; No.: ChiCTR-TRC-13003544; URL: http://www.chictr.org.cn/abouten.aspx.

Who Took Part

PubMed indexes the participants as teenagers, adults and middle-aged adults, both men and women.

Eligible participants were recruited and randomly assigned to receive acupuncture or auricular point pressing or NRT via a central randomization system with a 1:1:1 ratio.

All treatment was given for a total of 8 weeks, and follow-up visit was at 16 weeks.

How the Study Was Run

The researchers set it up as a randomized, open-label and multicenter study.

The participants were allocated by chance, so the Therapeutic nicotine (patch, non-peptide) group and the comparison group should start out alike.

Nothing was hidden in this open-label Therapeutic nicotine (patch, non-peptide) study: the participants and staff both knew the treatment.

More than one site took part, so the participants came from several places.

This randomized controlled trial was conducted in seven hospitals in China between October 2013 and February 2016.

The primary outcome measure was carbon monoxide (CO)-confirmed 24-h point abstinence rate (<10 parts per million), 24 weeks after quit day.

What Was Measured

Topics PubMed links to this paper include Acupuncture Therapy, China, Ear, External, Tobacco Use Cessation and Tobacco Use Cessation Devices.

The authors tagged it with the keywords nicotine replacement therapy, randomized controlled trial and tobacco cessation.

What This Means in Plain Language

The paper is a randomized, open-label and multicenter study of Therapeutic nicotine (patch, non-peptide).

Results are reported in around 6 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2018 (Chest), a journal based in United States.

More context: the Therapeutic nicotine (patch, non-peptide) compound page, all human trials.

Our Notes on the Compound

Therapeutic nicotine (patch, non-peptide): Pure nicotine as a signaling tool, separated from smoking and vaping.

Therapeutic nicotine (patch, non-peptide) in the library

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.