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Vaginal discharge concentrations of β-human chorionic gonadotropin, creatinine, and urea for the diagnosis of premature rupture of membranes

Plain-language guide to PMID 29197087 (2018): observational study of hCG (human chorionic gonadotropin) in 2015, women.

Key Facts

PMID
29197087
Journal
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
Year
2018
Study type
Observational Study
Authors
Bouzari Z et al. (6 authors)
DOI
10.1002/ijgo.12414

What This Study Did, in Plain Language

What Was Tested

The paper reports a study of hCG (human chorionic gonadotropin), published as an observational study.

To determine the diagnostic value of vaginal discharge concentrations of β human chorionic gonadotropin (β-hCG), creatinine, and urea to identify premature rupture of membranes (PROM).

Who Took Part

According to the abstract, 2015, women were involved.

PubMed indexes the participants as teenagers, young adults and adults, women only.

An observational cross-sectional study was conducted between 12 June, 2014, and 11 June, 2015, among 120 women who were admitted to an Iranian hospital at 28-41 weeks of pregnancy.

Women with positive pooling and nitrazine test results were assigned to the PROM group (n=60), whereas those with negative test results were assigned to the control group (n=60).

How the Study Was Run

Samples of vaginal discharge were obtained.

What Was Measured

PubMed files the paper under topics including Biomarkers, Chorionic Gonadotropin, beta Subunit, Human, Creatinine, Cross-Sectional Studies, Premature Rupture of Fetal Membranes, Hospitalization and Iran.

The authors tagged it with the keywords Premature rupture of membranes, Urea and β-human chorionic gonadotropin.

What This Means in Plain Language

This is an observational study of hCG (human chorionic gonadotropin) in 2015, women.

With several hundred people or more, it is a fairly large study for this kind of research.

The abstract goes on to report its results in about 4 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2018 (International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics), a journal based in United States.

More context: the hCG (human chorionic gonadotropin) compound page, all human trials.

Our Notes on the Compound

hCG (human chorionic gonadotropin): An LH analog that drives Leydig-cell testosterone production.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.