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Elevated parathyroid hormone levels after successful parathyroidectomy for primary hyperparathyroidism: a clinical review.

Plain-language guide to PMID 29209851 (2018): review of Parathyroid Hormone (PTH 1-84), hyperparathyroidism.

Key Facts

PMID
29209851
Journal
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
Year
2018
Study type
Review
Authors
de la Plaza Llamas R et al. (9 authors)
DOI
10.1007/s00405-017-4836-9

What This Paper Covers, in Plain Language

What It Covers

Researchers studied Parathyroid Hormone (PTH 1-84) in the context of hyperparathyroidism in this review publication.

Surgery for primary hyperparathyroidism (PHPT) is traditionally deemed to be successful if serum calcium levels return to normal 6 months after parathyroidectomy.

Regular monitoring of serum calcium and parathyroid hormone (PTH) in the follow-up of patients after parathyroidectomy for PHPT has drawn attention to the presence of a normocalcemic group of patients with elevated PTH (NCePTH) during the post-operative period.

How the Review Was Done

The researchers conducted an unlimited PubMed search updated on March 31, 2017, which yielded 1628 results.

What Was Measured

Surgery for primary hyperparathyroidism (PHPT) is traditionally deemed to be successful if serum calcium levels return to normal 6 months after parathyroidectomy.

Topics PubMed links to this paper include Adenoma, Calcifediol, Calcium, Hyperparathyroidism, Primary, Neoplasm Recurrence, Local, Parathyroid Hormone and Parathyroid Neoplasms.

The authors tagged it with the keywords Parathyroidectomy, Post-operative hyperparathyroidism, Post-operative period and Review.

What This Means in Plain Language

This is a review of Parathyroid Hormone (PTH 1-84) in people with hyperparathyroidism.

Its findings take up roughly 10 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2018 (European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery), a journal based in Germany.

More context: the Parathyroid Hormone (PTH 1-84) compound page, Hyperparathyroidism research.

Our Notes on the Compound

Parathyroid Hormone (PTH 1-84): The 84-amino-acid hormone that raises blood calcium; full-length PTH (Natpara) has been used in hypoparathyroidism. Teriparatide is its 1-34 fragment.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.