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The relationship of Physical performance and Osteoporosis prevention with vitamin D in older African Americans (PODA).
Plain-language guide to PMID 29221945 (2018): double-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc in 260 women.
Key Facts
- PMID
- 29221945
- Journal
- Contemporary clinical trials
- Year
- 2018
- Study type
- Randomized Controlled Trial
- Authors
- Dhaliwal R et al. (7 authors)
- DOI
- 10.1016/j.cct.2017.11.015
What This Study Did, in Plain Language
What Was Tested
The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a randomized controlled trial.
Objective measures of neuromuscular strength [Short Physical Performance Battery (SPPB), grip strength and 6-minute walking distance (6MWD)] and bone mineral density (BMD) were obtained.
Why It Was Studied
This information in older African Americans (AAs) is sparse.
Who Took Part
According to the abstract, 260 women were involved.
The age groups tagged for this paper are middle-aged adults and older adults, women only.
260 healthy AA women aged >60years were assigned to receive placebo or vitamin D3.
Subjects with baseline 25OHD levels ≤8ng/ml or ≥26ng/ml were excluded.
How the Study Was Run
In design terms this was a randomized, double-blind and placebo-controlled study.
Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.
As a double-blind Vitamin D, K2, Magnesium and Zinc study, the assignments were hidden from both participants and investigators until the end.
Some women received a placebo instead of Vitamin D, K2, Magnesium and Zinc, giving a reference point.
What Was Measured
Topics PubMed links to this paper include Black or African American, Body Weights and Measures, Bone Density, Calcifediol, Cholecalciferol, Health Behavior and Muscle Strength.
Author keywords: Free vitamin D, Physical performance and Vitamin D.
What This Means in Plain Language
The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc in 260 women.
The abstract goes on to report its results in about 6 sentences; this page does not restate them, so read the paper for the findings and their limits.
The publication is from 2018 (Contemporary clinical trials), a journal based in United States.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.