Effect of Monthly, High-Dose, Long-Term Vitamin D on Lung Function: A Randomized Controlled Trial.

What Was Tested

The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a randomized controlled trial.

The researchers examined effects of vitamin D supplementation on lung function.

At baseline and follow-up, spirometry yielded forced expiratory volume in 1 s (FEV1; primary outcome).

Who Took Part

The abstract describes 442 adults taking part.

The age groups tagged for this paper are middle-aged adults, older adults and people over 80, both men and women.

How the Study Was Run

The researchers set it up as a randomized, double-blind and placebo-controlled study.

Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

Blinding on both sides kept the adults and researchers unaware of who received Vitamin D, K2, Magnesium and Zinc.

A placebo (an inactive look-alike) gave the Vitamin D, K2, Magnesium and Zinc group a baseline to be compared against.

What Was Measured

At baseline and follow-up, spirometry yielded forced expiratory volume in 1 s (FEV1; primary outcome).

The subject headings attached to it are Asthma, Dietary Supplements, Forced Expiratory Volume, Lung, Pulmonary Disease, Chronic Obstructive, Spirometry and Vitamin D.

Author keywords: forced expiratory volume in 1 s, lung function and randomized controlled trial.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc in 442 adults.

With several hundred people or more, it is a fairly large study for this kind of research.

The publication is from 2017 (Nutrients), a journal based in Switzerland.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.