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Accelerated Titration of Oxytocin in Nulliparous Women with Labour Dystocia: Results of the ACTION Pilot Randomized Controlled Trial

Plain-language guide to PMID 29276166 (2018): double-blind randomized controlled trial study of Oxytocin in 79 women.

Key Facts

PMID
29276166
Journal
Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC
Year
2018
Study type
Randomized Controlled Trial
Authors
Dy J et al. (10 authors)
DOI
10.1016/j.jogc.2017.08.046

What This Study Did, in Plain Language

What Was Tested

The paper reports a study of Oxytocin, published as a randomized controlled trial.

Who Took Part

According to the abstract, 79 women were involved.

By PubMed's age tags, the people studied were adults, women only.

How the Study Was Run

In design terms this was a randomized, double-blind, multicenter, parallel-group and pilot study.

Because people in this Oxytocin study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

As a double-blind Oxytocin study, the assignments were hidden from both participants and investigators until the end.

Running at several centres spread the Oxytocin study over different clinics and patient groups.

Groups ran in parallel: each of the women stayed in one arm throughout.

This was a multicentre, double-masked, parallel-group pilot RCT.

This study was conducted in three Canadian birthing centres.

An intention-to-treat analysis was applied.

What Was Measured

PubMed files the paper under topics including Canada, Cesarean Section, Dystocia, Ethnicity, Oxytocin, Patient Satisfaction and Pilot Projects.

The authors tagged it with the keywords Caesarean section, labour augmentation, labour dystocia and randomized controlled trial.

What This Means in Plain Language

The paper is a randomized, double-blind and multicenter study of Oxytocin in 79 women.

Its findings take up roughly 4 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2018 (Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC), a journal based in Netherlands.

More context: the Oxytocin compound page, all human trials.

Our Notes on the Compound

Oxytocin: A peptide hormone with established obstetric medical uses and a less settled role in research on behavior, sexual function and appetite.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.