Intravenously Administered Lidocaine and Magnesium During Thyroid Surgery in Female Patients for Better Quality of Recovery After Anesthesia.

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc in this randomized controlled trial publication.

The researchers compared the quality of recovery 40 (QoR-40) scores of female patients who received intravenous lidocaine, magnesium, and saline during thyroidectomy to investigate their effects on comprehensive recovery from anesthesia.

Who Took Part

The abstract describes 135 patients taking part.

PubMed indexes the participants as young adults, adults, middle-aged adults and older adults, women only.

In this prospective, double-blind trial, 135 female patients scheduled for open thyroidectomy were randomly assigned to the lidocaine group (group L), magnesium group (group M), or control group (group C).

How the Study Was Run

The design is described as randomized and double-blind.

The patients were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.

Neither the patients nor the staff measuring them knew who was on Vitamin D, K2, Magnesium and Zinc, so expectations could not easily colour the readings.

Group C received an equivalent volume of saline.

The QoR-40 survey was conducted on postoperative days 1 and 2.

What Was Measured

Topics PubMed links to this paper include Administration, Intravenous, Analgesics, Anesthesia Recovery Period, Anesthetics, Local, Intraoperative Care, Lidocaine and Magnesium.

What This Means in Plain Language

The paper is a randomized and double-blind study of Vitamin D, K2, Magnesium and Zinc in 135 patients.

Its findings take up roughly 4 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2018 (Anesthesia and analgesia), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.